UBE2L3 Protein (AA 1-154)
Aperçu rapide pour UBE2L3 Protein (AA 1-154) (ABIN666841)
Antigène
Voir toutes UBE2L3 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 1-154
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Séquence
- MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQPEHP LRADLAEEYS KDRKKFCKNA EEFTKKYGEK RPVD
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Attributs du produit
- Ubc7(Ubiquitin Conjugating enzyme 7) Human Recombinant, expressed in E.coli
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Purification
- > 95% by SDS-PAGE
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 50 mM HEPES buffer ( pH 7.4) containing 150 mM NaCl, 1 mM DTT, 10 % glycerol
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
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Autre désignation
- UbcH7/UBE2L3
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Sujet
- Human ubquitin-conjugating enzyme 7 (ubcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-kappa B maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes (E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human uBE2L1-uBE2L4 gene could potentially encode different isoforms of the ubcH7. uBE2L3 gene, located at chromosome 22q11. 2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of ubcH7. ubcH7 (154amino acid) was over-expressed in E. coli and purified by using conventional chromatography techniques.
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Poids moléculaire
- 17.9 kDa (154aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_003338
Antigène
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